SAGRA-4U
Benzophenanthridine Alkaloids

COMPOSITION: Naturally occuring benzophenanthridine alkaloids:              Exipient: di H2O

PROPERTIES:
SAGRA-4U is antineoplastic: induces apoptosis in malignant cells
and is an immuno stimulant of cell medicated immunity.

THERAPEUTIC INDICATIONS:
For the treatment chemoresistant malignancies (cancer), with or without viral ethiology. SAGRA-4U upregulates the expression of the pro-apoptotic protein Bax and downregulates the expression of the anti-apoptotic protein bcl-2 in malignant cancer cells.
SAGRA-4U activates the cell mediated (CD-8 ans NK cells) immune response to malignant cells by unknown mechanisms.

DOSSAGE AND ADMINISTRATION:
SAGRA-4U is intended for the treatment of metastatic malignancies. Can be administered orally, diluted with 30 cc's of water 1 hr. before morning meal. Patients with WHO improved status may be treated via i.v. route directly, once dayly. Treatment should be continued for 20 days and the WHO performance status should be evaluated by a professional health care worker or physician.
Treatment course may be repeated once monthly.

ADVERSE EFFECTS:
None reported by day.

INCOMPATIBILITIES:
Not recommended for administration in conjuction with confentional toxic chemotherapeutic agents; during pragnancy or lactation period.

DELIVERY CONDITIONS:
This phytomedicine has been prescribed for You personally in specific conditions. Do not use except on medical advise.

STORAGE:
Store in non-freezing conditions (0 - 30 degree C).

STABILITY:
5 YEARS.

PACKING:
10 ampules/vials per package.

BIOSOME LABORATORIES INC.
3023 N. Oakland Av., Milwaukee, WI USA 53211